Equivalent to Excsep® C18

Phenomenex

Product Name: Luna® C18(2)

Functional Group: Octadecyl
Base Material: Fully porous high-purity silica
Particle Size: 1.6, 3, 5 & 10 μm
Pore Size: 100 Å
Surface Area: 400 m²/g
Carbon Loading: 17.5 %
End-Capping: Yes
Pressure Limit: 5 μm - 6000 psi; 3 μm - 9000 psi; 1.6 μm - 15000 psi
Temperature Limit: 60℃
pH Range: 1.5-10
Aqueous Compatibility: 100% water
Why It’s Equivalent: Matches C18 chemistry, offers similar particle sizes (including UHPLC-capable 1.6 μm), and has comparable carbon loading. Slightly smaller pore size (100 Å vs. 120 Å) and higher surface area may enhance retention for smaller molecules, while broader pH range adds flexibility.

Waters

Product Name: XBridge® BEH C18

Functional Group: Octadecyl
Base Material: Ethylene bridged hybrid (BEH) silica
Particle Size: 1.7, 2.5, 3.5 & 5 μm
Pore Size: 130 Å
Surface Area: 185 m²/g
Carbon Loading: 18 %
End-Capping: Yes
Pressure Limit: 5 μm - 6000 psi; 3.5 μm - 9000 psi; 1.7 μm - 18000 psi
Temperature Limit: 80℃ (low pH), 60℃ (high pH)
pH Range: 1-12
Aqueous Compatibility: 100% water
Why It’s Equivalent: Similar C18 functionality and particle size range, with a hybrid silica base that boosts pH stability (1-12 vs. 2-8). Slightly larger pore size (130 Å) and lower surface area suit broader analyte sizes, and high pressure tolerance (18000 psi) exceeds Excsep® for UHPLC use.

Agilent Technologies

Product Name: Poroshell 120 EC-C18

Functional Group: Octadecyl
Base Material: Superficially porous silica (core-shell)
Particle Size: 1.9, 2.7 & 4 μm
Pore Size: 120 Å
Surface Area: 130 m²/g
Carbon Loading: 10 %
End-Capping: Yes (double end-capped)
Pressure Limit: 4 μm - 6000 psi; 2.7 μm - 9000 psi; 1.9 μm - 18000 psi
Temperature Limit: 60℃
pH Range: 2-9
Aqueous Compatibility: 100% water
Why It’s Equivalent: Exact pore size match (120 Å) and C18 chemistry, with core-shell technology offering higher efficiency at lower carbon loading (10% vs. 17%). Particle sizes align well (1.9 μm for UHPLC), though temperature limit is lower (60℃ vs. 80℃).

Thermo Fisher Scientific

Product Name: Accucore™ C18

Functional Group: Octadecyl
Base Material: Superficially porous silica (core-shell)
Particle Size: 2.6 & 4 μm
Pore Size: 80 Å
Surface Area: 130 m²/g
Carbon Loading: 9 %
End-Capping: Yes
Pressure Limit: 4 μm - 6000 psi; 2.6 μm - 14500 psi
Temperature Limit: 70℃
pH Range: 2-9
Aqueous Compatibility: 100% water
Why It’s Equivalent: Core-shell C18 design offers high efficiency, with particle sizes suitable for HPLC and UHPLC. Smaller pore size (80 Å) and lower carbon loading (9%) may reduce retention compared to Excsep®, but pressure and pH ranges are comparable.